We offer FTE based or Fee-for service in 4 key areas:
1) Medicinal and Synthetic Chemistry
i. Small molecule syntheses
ii. Scale-up and synthetic process development
iii. Microchannel reactions and continuous flow process development
iv. Heterocyclic molecule syntheses
v. Carbohydrate syntheses
vi. Peptide syntheses
vii. Lipid and LNP syntheses
viii. HPLC purifications
ix. Antibody-drug conjugates (ADCs )
x. PROTAC drug discovery and development
xi. Polymer syntheses
xii. API syntheses
xiii. Design and synthesis of analogs or focused libraries
xiv. SAR studies and lead optimizations
2) Molecular Modeling
i. Protein dynamics
ii. Protein-ligand docking Molecular Modeling of Ligand-Protein Interactions
iii. proprietary compound design
iv. Novel derivatives generating
3) Computer Assisted Drug Discovery and Development
i. Proprietary software-based prediction of toxicity, ADME and PK
ii. Generation of analogues to cover chemical space for IP Protection
4) Biochemistry
i. Protein biochemistry and molecular mechanism to discover protein targets
ii. Evaluation of cellular mechanism using associated cell-based assays
iii. Protein analysis and proteomics
We operate out of a >10,000 square feet laboratory space with equipment for
• mg to kg scale chemical synthesis
• Enzyme catalyzed reactions
• Continuous flow microchannel reactions
• Peptide synthesis
• Complex HPLC purification
• NMR analysis
Mass Spectrometry
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